ESPE Abstracts

Familial clustering of type-2 diabetes is well-known. In adults, the prevalence of diabetes is higher among patients with diabetic parents. The Framingham offspring study found that maternal and paternal diabetes conferred equal risk for offspring type-2 diabetes.Objectives: We conducted this study to compare the clinical characteristics of children and adolescents with family history of type- 2 diabetes mellitus, in one or both parents,...

The incidence of both type 1 (T1DM) and type 2 diabetes (T2DM) has shown a rise in Qatar in parallel with a notable increase in the incidence of a new expression of the disease in children and adolescents, with the characteristics of a mixture of the two types of diabetes and referred to as ’double diabetes’ (DD). Insulin resistance and obesity, together with the presence of markers of pancreatic autoimmunity - namely, autoantibodies to islet cell antigens - typicall...

Background: Continuous Glucose Monitoring (CGMS) is a useful method to detect the variability of glucose fluctuations and offers the opportunity for better assessment of glucose homeostasis in TM patients and response to therapy.Objective and hypotheses: Does real-life monitoring of blood glucose add to the therapeutic approach to patients with TM who have glycemic abnormalities?Method: In two thalassemic adolescents with glycemic ...

Studies support the existence of a genetic contribution to both type 1 and type 2 diabetes, and additionally suggest a relationship between both types of diabetes. The rapidly growing worldwide epidemic of type 2 diabetes has been partially explained by obesity and the sedentary lifestyle. However, familial factors also seem to play a major role in the pathogenesis of type 2 diabetes.). The fact that type 1 and type 2 diabetes cluster in families suggests that some patients ma...

Hypothyroidism is prevalent among pediatric patients with T1DM and is associated with a more aggressive form of the disease. Patients with T1DM and hypothyroidism have higher rates of DKA, develop the disease at younger ages, and require higher insulin doses. T2DM patients are also more prone to thyroid disorders. The prevalence of thyroid dysfunction in adults with T2DM patients was reported to be 12.3% in Greece and 16% in Saudi Arabia and has been reported to be associated ...